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Le modafinil est un composГ© racГ©mique, ce qui signifie qu'il y a des quantitГ©s Г©gales de molГ©cules gauchers et droitiers dans le corps. Les patients prenant ces mГ©dicaments sont susceptibles de voir un effet pharmacologique additif Г la suite de l'interaction de l'agent Modafinil-CNS. Le modafinil a Г©tГ© Г©tudiГ© pour son efficacitГ© en tant que stimulant cognitif chez les personnes en bonne santГ© et les personnes handicapГ©es. Le modafinil active les transporteurs de dopamine dans plusieurs rГ©gions du cerveau. Modafinil est utilisГ© avec les conseils d'un psychiatre et d'autres mГ©dicaments pour traiter ces conditions. Modalert Canada Le modafinil est un petit composГ© organique qui est un analogue direct de l'amphГ©tamine. On ne pense pas que cette action soit due Г l'interaction spГ©cifique du modafinil avec des cibles spГ©cifiques dans le cerveau, mais plutГґt Г un changement gГ©nГ©ral de l'Г©quilibre excitation/inhibition du cerveau, qui Г son tour affecte les temps d'attention et de rГ©action. Seules des doses plus Г©levГ©es de modafinil prГ©viennent de maniГЁre fiable la somnolence. Le mГ©dicament modifie l'activitГ© des neurones dans les parties du cerveau qui sont responsables de diverses fonctions cognitives. Il provoque une augmentation de la production de noradrГ©naline dans le cerveau, afin de l'amГ©liorer, le mГ©dicament est pris le matin. Les deux agissent par des mГ©canismes diffГ©rents. Le dosage pharmaceutique global est de 200 mg. Le modafinil est contre-indiquГ© chez les patients atteints de glaucome Г angle fermГ©, de myasthГ©nie grave et chez ceux qui prennent de la clozapine. Le modafinil est utilisГ© pour traiter la somnolence diurne excessive (EDS) due Г l'apnГ©e obstructive du sommeil, Г la narcolepsie et aux troubles du travail postГ©. La version nasale est un traitement efficace pour ceux qui trouvent que leur mГ©dicament principal ne produit pas d'avantages notables. La narcolepsie peut ГЄtre dГ©clenchГ©e par la rougeole ou les oreillons, ou ГЄtre hГ©rГ©ditaire. En tant que mГ©dicament sur ordonnance de l'annexe IV ou, dans certains cas limitГ©s (reportez-vous Г la page d'informations sur les ordonnances pour en savoir plus) en vente libre aux Г‰tats-Unis, le modafinil est bien compris comme un mГ©dicament sur ordonnance uniquement dont les produits sont fabriquГ©s en nombres trГЁs limitГ©s et autorisГ©s Г ГЄtre utilisГ©s par certains professionnels de la santГ©. Il se lie au site actif du transporteur de recapture de la dopamine.
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