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Acheter Modiodal Generique
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Le médicament a été testé dans plus de 120 essais humains bien conçus. Les pilules n'ont pas besoin d'être écrasées ou dissoutes avant utilisation, ce qui les rend plus faciles à prendre que de nombreux autres somnifères sur ordonnance et en vente libre. Il est également à l'étude comme traitement possible pour les personnes atteintes de trouble d'hyperactivité avec déficit de l'attention et de la maladie d'Alzheimer et peut être utilisé comme stimulant cognitif pour améliorer l'éveil chez les personnes souffrant de dépression et les personnes qui se remettent d'une perte de sommeil sévère. Le modafinil ne corrige pas les personnes souffrant d'un trouble du sommeil lié au rythme circadien sous-jacent et, dans une étude, n'a pas amélioré les symptômes du somnambulisme. Le modafinil est un inhibiteur sélectif, réversible et de haute affinité de la recapture dopaminergique. Cependant, le modafinil semble stimuler les zones cérébrales impliquées dans le cycle du sommeil. Les enzymes PDE régulent les niveaux d'adénosine monophosphate cyclique (AMPc) dans le corps. Acheter Modiodal Generique substance. Maux de tête, tremblements et nausées sont quelques-uns des effets secondaires signalés. Le modafinil est administré par voie orale sous forme de comprimés de 200 mg ou 400 mg. On pense qu'il augmente le nombre de cycles veille-sommeil, ralentissant la libération de sérotonine et de mélatonine induisant le sommeil. Les effets secondaires légers comprennent des étourdissements, des maux de tête et des nausées. La substance active est un mélange racémique de D- et L-thréo-modafinil. Les patients prenant des médicaments qui stimulent le cytochrome P450 CYP3A4 (par exemple, la rifampicine, la rifabutine) peuvent présenter une augmentation des effets secondaires tels que des maux de tête, une dyspepsie ou des nausées. Provigil Modafinil Son efficacité n'est pas affectée par la cataplexie. Il est rapidement absorbé par l'organisme et métabolisé dans le foie en métabolites inactifs. Le modafinil et d'autres médicaments similaires agissent sur les mêmes récepteurs du système nerveux central que le neurotransmetteur dopamine. Il est commercialisé sous diverses marques, notamment Armodafinil, Armodafinil R, Armodafinil XP, Modavigil et Modavigil Forte. Le modafinil doit être utilisé avec prudence chez les femmes enceintes, en particulier au cours du deuxième ou du troisième trimestre. Étant donné que ces doses sont supérieures à la dose quotidienne maximale approuvée de 400 mg, il existe un certain risque d'effets indésirables à ces doses élevées. Son efficacité est discutable en raison du manque de preuves dans ce domaine.
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